Vancomycin-specific T Cell responses in allergic and non-allergic individuals
نویسندگان
چکیده
Background The association between specific HLA alleles and risk of severe cutaneous drug hypersensitivity reactions is increasingly recognised. Vancomycin mediated pseudo-allergic ‘red man syndrome’ is well recognised, yet urticaria/anaphylaxis is uncommon and some clinical reactions are delayed. Although this may suggest the presence of vancomycin initiated T cell responses, no predisposing vancomycin HLA association has been identified. Therefore we set out to examine the role of T cell responses in vancomycin hypersensitivity reactions.
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